PEPTIDE THERAPY
mimics natural signals in the body
to support healing, resilience, and healthy aging of your pet.
PEPTIDE THERAPY
introduction
Welcome to Earth Medicine's Peptide Therapy. This gentle therapy helps reawaken your pet's innate healing responses—supporting tissue repair, resilience, and overall well-being in a way that aligns with the body’s natural intelligence.
Please review this page before booking a consultation with me. You will find four guiding sections below:
PEPTIDE THERAPY 101
Peptide therapy uses short chains of amino acids that mimic natural signals in the body to support healing, resilience, and healthy aging. Because they align with normal biology, peptides can sometimes provide targeted effects with comparatively small doses.
WHAT ARE PEPTIDES?
Peptides are small proteins the body makes to communicate between cells. As pets age—or with stress, illness, or environmental exposures—those signals can decline. Therapeutic peptides aim to gently “remind” tissues how to heal and regulate.
HOW ARE PEPTIDES GIVEN?
In our practice, peptides are given as tiny subcutaneous injections (just under the skin). We teach you how to give them at home.
POTENTIAL BENEFITS (EXAMPLES):
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Support soft-tissue healing for lameness: (muscle injury, tendon injury, ACL ligament tears/ruptures).
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Gastrointestinal mucosal support for: (Inflammatory Bowel disease, chronic gastrointestinal issues.
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Allergies: (targeting the gastrointestinal system where the bulk of the immune system originates).
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Post-surgical recovery: (soft tissue and orthopedic rehabilitation).
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Support for aging pets: (osteoarthritis, mobility issues, resilience, strength, immune support).
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Immune balance and resilience: (for cancer support and geriatric support).
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We are also looking into the benefits of cycling this peptide 1-2 times per year for certain individuals.
FAQ's:
ARE PEPTIDES "NATURAL"?
Peptides (in peptide therapy) are short chains of amino acids—basically tiny pieces of
proteins—that the body naturally uses as signals to turn cellular processes on or off
(repair, calm inflammation, support immunity, etc.). In therapy, carefully selected
peptides are given in very small amounts to mimic those natural signals, aiming to
nudge the body’s own healing and regulation—not to replace normal functions.
HOW QUICKLY WILL WE SEE CHANGES?
Some families report shifts in 4-6 weeks for injuries and mobility issues. We set longer horizons, such as 3 months, for other healing.
WHAT ABOUT SIDE EFFECTS?
Peptides are usually well tolerated at micro-doses, but any bioactive compound can
cause reactions. We monitor and stop if needed. (Large, well-controlled safety data in
pets are still limited.) sciencedirect.com.
Although less common, minor side effects are redness or swelling at the injection site. If this continues, it is recommended to stop. Although rare, more moderate side effects are vomiting, diarrhea, trouble breathing, facial swelling, severe lethargy, or collapse—in these cases stop the peptide immediately and seek veterinary support.
ARE PEPTIDES LABELED FOR ANIMAL USE?
Some peptides are investigational/off-label and not FDA-approved for veterinary use.
HOW DO I STORE MY PET'S PEPTIDES?
Peptide vials are to be stored in the refrigerator away from light. Peptides are to be refrigerated at all times. If traveling you can put them on a cooler with an ice pack.
DO I REALLY NEED TO CLEAN THE TOP OF THE VIAL WITH ALCOHOL BEFORE EACH USE?
Yes, this assures there is no bacterial contamination. You can use a cotton ball with alcohol if you don’t have pads.
HOW DO I DISPOSE OF SYRINGES?O I REALLY NEED TO CLEAN THE TOP OF THE VIAL WITH ALCOHOL BEFORE EACH USE?
Dispose syringes in an FDA cleared sharps container. If you don’t have an FDA-cleared sharps container, you can use a heavy-duty household plastic container (e.g., an empty laundry-detergent bottle) temporarily and then take it to an approved drop-off. The container must be rigid, leak-resistant, puncture-resistant, with a tight screw cap, and clearly labeled (e.g., “SHARPS – DO NOT RECYCLE”).
You can also find nearby drop-offs via SafeNeedleDisposal’s Oregon page (lists Rogue Disposal and other programs). Safe Needle Disposal. Don’t put loose needles in the trash or recycling; don’t flush them.
HOW TO MAKE A SAFE DIY CONTAINER?
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Choose a thick plastic bottle with a screw-on cap (laundry-detergent/bleach). Don’t use thin plastic (e.g., water/soda bottles) or anything that can be punctured easily.
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Label clearly: “SHARPS – DO NOT RECYCLE.” (Write on the bottle.)
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Use immediately after each injection: drop needle/syringe in point-first; do not recap, bend, or break needles. CDC
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Fill only to ¾ full, then close and tape the cap securely.
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Store out of reach of children and pets.
INSTRUCTIONAL VIDEOS & IMAGES
For helpful support in administering peptides to your pet companion, below are a series of instructional videos and images. Please return to this information as you need.
PEPTIDE THERAPY CONSULTATION
A focused telemedicine or in-person visit to explore whether therapeutic peptides are a good fit for your pet—currently featuring BPC-157 (Body Protection Compound-157) and TB 500 (thymosin beta-4 (Tβ4) combined therapy. These are investigational peptides studied in preclinical models for tissue repair and resilience. Peptide Therapy is not intended to be used as a stand alone treatment or in place of medication and supportive modalities, but in conjunction with them and healthy lifestyle changes.
POTENTIAL USES OF BPC-157 & TB 500 IN COMBINATION:
GASTROINTESTINAL HEALING
May support gastric/intestinal mucosal integrity and comfort; often considered when GI lining support is a goal. This would benefit pets with Inflammatory bowel disease, environmental allergies, food allergies, chronic diarrhea, chronic vomiting, and other signs of GI upset or poor function.
SOFT-TISSUE INJURIES (LIGAMENTS, TENDONS, MUSCLE)
Adjunct treatment for strains, sprains, stifle injuries, elbow injuries and overuse injuries to support tissue repair alongside rest and rehabilitation. This would benefit pets with soft tissue injuries such as shoulder OCD and partial or complete rupture of the ACL in the knee, and a multitude of other musculoskeletal issues.
POST-SURGICAL RECOVERY (SOFT TISSUE OR ORTHOPEDIC)
Potential adjunct to conventional post-operative care to support tissue healing and comfort.
ACUTE SPINAL CORD INJURY (E.G., IVDD OR FCE)
Use alongside rest and conventional care; goals are comfort and neurologic support. This would benefit the pet with pain and/or paralysis.
GERIATRIC SUPPORT (OVERALL HEALTH & WELLBEING)
May be considered to support resilience, mobility, and recovery capacity in aging pets with osteoarthritis.
CANCER PATIENT SUPPORT (OVERALL HEALTH & WELLBEING)
Adjunct focus on comfort, immune support, resilience while undergoing chemotherapy or in conjunction with a more holistic approach to supporting pets with cancer.
HOW THE CONSULTATION WORKS:
1. Medical record review before we meet.
2. During your appointment, we discuss how peptide therapy may apply to your pet’s specific needs and answer questions.
3. If we agree peptide therapy is appropriate, I will recommend a protocol specifically for your pet and their needs. You will receive pricing for your pet’s plan and access to an instructional video on how to give the peptides as a subcutaneous injection. Peptides and supplies to get you started will then be mailed to you.
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REFERENCES &
FURTHER READING
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Clinical anecdotes/vet case literature: limited veterinary case reports exist (e.g., adjunct use for stifle injury), but no standardized veterinary dosing guidelines are established. ahvma.org
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Preclinical safety/toxicology including dogs. A GLP-style program reported BPC-157 was well tolerated in mice, rats, rabbits, and dogs (no serious toxicity; negative genetic and embryo-fetal findings). PubMed+1
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Dog pharmacokinetics. Beagle studies (single IV; single and repeated IM dosing) characterized PK/ADME in dogs (e.g., single IV 6 µg/kg; repeated IM 30 µg/kg ×7 days). pmc.ncbi.nlm.nih.gov
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Equine administration & detection. LC-MS/MS studies developed assays and confirmed detectability of TB-500 (N-acetyl-LKKTETQ) and metabolites in horse plasma/urine after administration—useful as hard evidence of veterinary use, albeit in a doping-control context rather than therapy. PubMed+2ScienceDirect+2
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Tβ4 animal-model review. Summarizes wound/tissue-repair effects across animal models (basis for TB-500 concept), but not veterinary clinical trials. PubMed
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FDA. “Certain Bulk Drug Substances for Use in Compounding… (BPC-157 listing).” (Updated 2025). U.S. Food and Drug Administration
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USADA/OPSS. “BPC-157: Prohibited peptide and unapproved drug.” (2025). opss.org+
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Hsieh MJ, et al. Sci Rep 2020: BPC-157 and NO-mediated vasodilation. Nature
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Xu C, et al. Toxicol Appl Pharmacol 2020: Preclinical safety across species. sciencedirect.com
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Vasireddi N, et al. Sports Health 2025: Orthopedic review of BPC-157. SAGE Journals
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McGuire FP, et al. 2025 review: Angiogenesis/VEGFR2/Akt-eNOS pathways. PMC
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He L, et al. 2022 PK: proposed microgram-scale dose exploration, including dog PK. PMC
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Research & Markets (2020): ~807 peptide drugs in trials; ~197 marketed (market analysis). Business Wire
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Soft-tissue & wound repair: Animal models and reviews report faster closure and improved quality of dermal and musculoskeletal healing; small human trials with topical Tβ4 suggested accelerated wound healing. Evidence for systemic TB-500/Tβ4 in controlled human trials remains limited. PMC+1
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Other tissues: Preclinical signals in muscle, tendon/ligament, bone, nerve, and GI mucosa; translation to standardized clinical dosing is unresolved. PMC
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Early clinical safety work: Phase 1/2 investigations with Tβ4 (not TB-500) examined IV/topical use and general tolerability, but did not establish approved indications. ClinicalTrials+1
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Classified as prohibited by anti-doping authorities (USADA/WADA) and noted by other regulators (e.g., TGA) as an unapproved growth-factor peptide. Use is off- label/investigational. NPC Hello+2Wada-Ama+2
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Angiogenesis & endothelial support via VEGFR2/Akt/eNOS pathways; modulation of nitric oxide signaling. PMC+1
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Anti-inflammatory and cytoprotective actions across multiple injury models. SAGE Journals
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Narrative and scoping reviews summarize improved healing in tendon/ligament, muscle, bone, and GI mucosa models, with encouraging signals but limited controlled human data to date. SAGE Journals+1
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Safety (preclinical): multi-species toxicology work (mice, rats, rabbits, dogs) reported good tolerability at tested doses; human clinical safety remains insufficiently characterized. sciencedirect.com
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Pharmacokinetics: early studies (including dog PK) explore exposure at microgram-scale dosing; translation to clinical veterinary dosing remains investigational. PMC
This information is educational and not a substitute for individualized veterinary advice.
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